Comparing EEG patterns of actual and imaginary wrist movements - a machine learning approach

Our goal is to develop an algorithm for feature extraction and classification to be used in building brain-computer interfaces. In this paper, we present preliminary results for classifying EEG data of imaginary wrist movements. We have developed an algorithm based on the spatio-temporal features of the recorded EEG signals. We discuss the differences between the feature vectors selected for both actual and imaginary wrist movements and compare classification results

Neural spike train synchronization indices: Definitions, interpretations, and applications

A comparison of previously defined spike train synchronization indices is undertaken within a stochastic point process framework. The second-order cumulant density (covariance density) is shown to be common to all the indices. Simulation studies were used to investigate the sampling variability of a single index based on the second-order cumulant. The simulations used a paired motoneurone model and a paired regular spiking cortical neurone model. The sampling variability of spike trains generated under identical conditions from the paired motoneurone model varied from 50% to 160% of the estimated value. On theoretical grounds, and on the basis of simulated data a rate dependence is present in all synchronization indices. The application of coherence and pooled coherence estimates to the issue of synchronization indices is considered. This alternative frequency domain approach allows an arbitrary number of spike train pairs to be evaluated for statistically significant differences, and combined into a single population measure. The pooled coherence framework allows pooled time domain measures to be derived, application of this to the simulated data is illustrated. Data from the cortical neurone model is generated over a wide range of firing rates (1-250 spikes/s). The pooled coherence framework correctly characterizes the sampling variability as not significant over this wide operating range. The broader applicability of this approach to multielectrode array data is briefly discussed

A comparative study of four novel sleep apnoea episode prediction systems

The prediction of sleep apnoea and hypopnoea episodes could allow treatment to be applied before the event be-comes detrimental to the patients sleep, and for a more spe-cific form of treatment. It is proposed that features extracted from breaths preceding an apnoea and hypopnoea could be used in neural networks for the prediction of these events. Four different predictive systems were created, processing the nasal airflow signal using epoching, the inspiratory peak and expiratory trough values, principal component analysis (PCA) and empirical mode decomposition (EMD). The neu-ral networks were validated with naïve data from six over-night polysomnographic records, resulting in 83.50% sensi-tivity and 90.50% specificity. Reliable prediction of apnoea and hypopnoea is possible using the epoched flow and EMD of breaths preceding the event

Implementation and evaluation of different time and frequency domain feature extraction methods for a two class motor imagery BCI applications : a performance comparison between GPU and CPU

OpenCL platform is widely used in high-performance computing such as multicore CPUs, GPUs, or other accelerators [1] which employed heterogeneous computing concept resulting in execution acceleration. As the advantages of parallel computing, it has been applied to brain-computer interface (BCI) applications especially speeding up signal processing pipelines such as feature selection [2]. In this study, we used OpenCL to implement some feature extraction methods on a IEEE open-access dataset [3] which provides 2-class motor imagery EEG recordings. Different feature extraction methods including template matching, statistical moments, selective bandpower and fast Fourier transform power spectrum were selected to evaluate their computational performance on both CPU and GPU using OpenCL. This study used an open-access dataset that contains data presenting a 2-class motor imagery tasks. The dataset used to compare the performance of proposed feature extraction approaches in terms of accuracy and computation time. The study processed following a standard signal processing pipeline including pre-processing for artifact rejection, feature extraction, and classification. The preliminary results show that running feature extraction methods on GPU yields a computing speed up at least to five times compared to CPU. In addition, amending parameters of parallel computing such as the number of work-items or work-groups could reduce computing time more. The complexity of the proposed algorithm can be assessed by the heterogeneous computing concept. Fine-tuning the parameters of parallel computing and system optimization could increase the performance

The influence of central neuropathic pain in paraplegic patients on performance of a motor imagery based brain computer interface

The aim of this study was to test how the presence of central neuropathic pain (CNP) influences the performance of a motor imagery based Brain Computer Interface (BCI). In this electroencephalography (EEG) based study, we tested BCI classification accuracy and analysed event related desynchronisation (ERD) in 3 groups of volunteers during imagined movements of their arms and legs. The groups comprised of nine able-bodied people, ten paraplegic patients with CNP (lower abdomen and legs) and nine paraplegic patients without CNP. We tested two types of classifiers: a 3 channel bipolar montage and classifiers based on common spatial patterns (CSPs), with varying number of channels and CSPs. Paraplegic patients with CNP achieved higher classification accuracy and had stronger ERD than paraplegic patients with no pain for all classifier configurations. Highest 2-class classification accuracy was achieved for CSP classifier covering wider cortical area: 82 ± 7% for patients with CNP, 82 ± 4% for able-bodied and 78 ± 5% for patients with no pain. Presence of CNP improves BCI classification accuracy due to stronger and more distinct ERD. Results of the study show that CNP is an important confounding factor influencing the performance of motor imagery based BCI based on ERD

Top Compositeness at the Tevatron and LHC

We explore the possibility that the right-handed top quark is composite. We examine the consequences that compositeness would have on $t \bar{t}$ production at the Tevatron, and derive a weak constraint on the scale of compositeness of order a few hundred GeV from the $t \bar{t}$ inclusive cross section. More detailed studies of differential properties of $t \bar{t}$ production could potentially improve this limit. We find that a composite top can result in an enhancement of the $t \bar{t} t \bar{t}$ production rate at the LHC (of as much as $10^3$ compared to the Standatd Model four top rate). We explore observables which allow us to extract the four top rate from the backgrounds, and show that the LHC can either discover or constrain top compositeness for wide ranges of parameter space.Comment: 9 pages, 4 figure

Shrinking a large dataset to identify variables associated with increased risk of Plasmodium falciparum infection in Western Kenya

Large datasets are often not amenable to analysis using traditional single-step approaches. Here, our general objective was to apply imputation techniques, principal component analysis (PCA), elastic net and generalized linear models to a large dataset in a systematic approach to extract the most meaningful predictors for a health outcome. We extracted predictors for Plasmodium falciparum infection, from a large covariate dataset while facing limited numbers of observations, using data from the People, Animals, and their Zoonoses (PAZ) project to demonstrate these techniques: data collected from 415 homesteads in western Kenya, contained over 1500 variables that describe the health, environment, and social factors of the humans, livestock, and the homesteads in which they reside. The wide, sparse dataset was simplified to 42 predictors of P. falciparum malaria infection and wealth rankings were produced for all homesteads. The 42 predictors make biological sense and are supported by previous studies. This systematic data-mining approach we used would make many large datasets more manageable and informative for decision-making processes and health policy prioritization

Global Search for New Physics with 2.0/fb at CDF

Data collected in Run II of the Fermilab Tevatron are searched for indications of new electroweak-scale physics. Rather than focusing on particular new physics scenarios, CDF data are analyzed for discrepancies with the standard model prediction. A model-independent approach (Vista) considers gross features of the data, and is sensitive to new large cross-section physics. Further sensitivity to new physics is provided by two additional algorithms: a Bump Hunter searches invariant mass distributions for "bumps" that could indicate resonant production of new particles; and the Sleuth procedure scans for data excesses at large summed transverse momentum. This combined global search for new physics in 2.0/fb of ppbar collisions at sqrt(s)=1.96 TeV reveals no indication of physics beyond the standard model.Comment: 8 pages, 7 figures. Final version which appeared in Physical Review D Rapid Communication

Observation of Orbitally Excited B_s Mesons

We report the first observation of two narrow resonances consistent with states of orbitally excited (L=1) B_s mesons using 1 fb^{-1} of ppbar collisions at sqrt{s} = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. We use two-body decays into K^- and B^+ mesons reconstructed as B^+ \to J/\psi K^+, J/\psi \to \mu^+ \mu^- or B^+ \to \bar{D}^0 \pi^+, \bar{D}^0 \to K^+ \pi^-. We deduce the masses of the two states to be m(B_{s1}) = 5829.4 +- 0.7 MeV/c^2 and m(B_{s2}^*) = 5839.7 +- 0.7 MeV/c^2.Comment: Version accepted and published by Phys. Rev. Let

Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set

We report a measurement of the bottom-strange meson mixing phase \beta_s using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays in which the quark-flavor content of the bottom-strange meson is identified at production. This measurement uses the full data set of proton-antiproton collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity. We report confidence regions in the two-dimensional space of \beta_s and the B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2, -1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in agreement with the standard model expectation. Assuming the standard model value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +- 0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +- 0.009 (syst) ps, which are consistent and competitive with determinations by other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012